2019 — 2023 · 5 modifications
| Modification | Power | 0–100 km/h | Drive | Gearbox |
|---|---|---|---|---|
| GLS350d 3.0 AT 4Matic | 286 hp | 7 s | tdr-4x4 | trans-automatic |
| GLS400d 3.0 AT 4Matic | 330 hp | 6.3 s | tdr-4x4 | trans-automatic |
| GLS450 3.0 AT EQ Boost 4Matic | 367 hp | 6.2 s | tdr-4x4 | trans-automatic |
| GLS450 3.0 AT EQ Boost 4Matic | 362 hp | 6.2 s | tdr-4x4 | trans-automatic |
| GLS580 4.0 AT EQ Boost 4Matic | 489 hp | 5.3 s | tdr-4x4 | trans-automatic |